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islandjanin- 01-30-2008
Pomoć Oko Stručnog Medicin. Teksta!
Ja imam jednu veeeeliku molbu za one koji znaju engleski! Naime, potreban mi je prevod ovog teksta, a ja se ne usuđujem da se upustim u prevođenje... Dakle, ako ima nekog ovde ko ima malo vremena i volje da mi pomogne biću mu iskreno zahvalan! Studies comparing human maternal and umbilical cord blood cadmium levels are inconsistent, but for most studies fetal umbilical cord blood cadmium levels range from 40% to 70% maternal levels…., indicating that the placenta acts as a barrier to fetal exposure to cadmium. The divergent results may reflect methodological problems in measurement of low levels of cadmium. The mechanism and factors involved in the retention of cadmium by the placenta are not well defined. The most plausible explanation is that cadmium is retained by binding to metallothionein and/or other compounds at specific sites in the placenta. The presence of metallothionein has been demonstrated in human placenta and fetal membranes….. Synthesis can also be induced in cultured human trophoblasts by both cadmium and zinc salts. The syncytiotrophoblasts has been shown to be the site of metallothionein synthesis, a protein that binds cadmium and may also enhance transport of essential trace metals zinc and cooper…. Metallothionein mRNA is increased in spongiotrophoblasts of mouse placenta following injection of cadmium and zinc… Constitutively high levels of metallothionien and mRNA are also detected in the deciduum following early implantation. Using a cytohistochemistry technique and antibody to metallothionein in the amniotic membrane, in syncytical trophoblasts, in interstitial cells within the villi, and in maternal decidual cells of human placenta.

islandjanin- 01-31-2008

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